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Latest in Stem Cell Research

  • A team of researchers at the Washington University School of Medicine in St. Louis have converted human stem cells into insulin-producing cells, controlling the blood sugar levels of laboratory mice. Within just nine months, the mice had been cured of diabetes, hinting that the procedure may be used in humans to cure diabetes. Published in […]

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  • Preterm birth and its complications are the leading cause of neonatal death. The main underlying pathological mechanisms for preterm complications are disruption of the normal maturation processes within the target tissues, interrupted by premature birth. Cord blood, as a new and convenient source of stem cells, may provide new, promising options for preventing preterm complications. […]

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  • Benefits of cord blood transplantation include low rates of relapse and chronic graft-versus-host disease (GVHD). However, the use of cord blood is rapidly declining because of the high incidence of infections, severe acute GVHD, and transplant-related mortality. UM171, a haematopoietic stem cell self-renewal agonist, has been shown to expand cord blood stem cells and enhance […]

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  • Intravenous infusion of banked autologous and sibling umbilicalcord blood (CB) is being studied in children with acquired neu-rological conditions and has demonstrated safety and feasibilityin phase I/II studies. To provide access to this investigationalprocedure while efficacy trials are conducted, an expandedaccess program (EAP) was developed. More than 1,400 children have enrolled in the screening protocol […]

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  • A study released in STEM CELLS Translational Medicine provides compelling evidence of how an injection of human amniotic fluid stem cells can be used to protect the spinal cord of a fetus from myelomeningocele (MMC). The finding could lead to a new strategy for treating this debilitating birth defect that affects about 1 out of […]

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  • An 8-month-old girl who had severe combined immune deficiency (SCID) underwent a successful hematopoietic stem cell transplant surgery at the Children’s Hospital of Fudan University in Shanghai; the stem cell was taken from umbilical cord blood. The baby girl, identified by the hospital as Ranbao, started to develop symptoms including cough, fever, swollen lymph node and […]

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  • The baby girl Zhao Jiaxin was the first child in China to receive a cord blood transplant as a cure for a genetic form of irritable bowel disease that is often lethal to newborns.   Born in early 2015, baby Zhao began suffering from diarrhea and fever when she was just 8 days old. These […]

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  • Epileptic seizures could be halted by injecting stem cells into the brain, scientists claim. Researchers have developed a new treatment, which involves converting skin cells into stem cells – which can turn into any type.  The converted stem cells, designed to dampen down the effects of seizures, are then implanted back into the brain. The […]

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  • An international study published in the journal Blood by researchers led by Dr. Elie Haddad, a pediatric immunologist and researcher at CHU Sainte-Justine and professor at Université de Montréal, highlights the urgent need to develop better treatment strategies for patients suffering from severe combined immune deficiency (SCID). This deficiency, better known as “bubble baby disease” […]

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  • Performed as part of reconstructive surgery when the infant is a few months old, the stem cell procedure provides good results in growing new bone to close the upper jaw cleft — and may avoid the need for later bone graft surgery, according to the case report by Alejandro Garcia Botero, MD, of Hospital De […]

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  • According to the Duke Center for Autism, “previous research has shown that cord blood cells can help reduce inflammation and signal cells to help repair damaged brain areas. The goal of this study was to investigate whether similar success will be shown in children with ASD.” “But the study is blinded, so no one knows […]

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  • Four-year-old Wyatt Haney has been fighting for his life since the day he was born at a Joplin, Mo., hospital. 11 months after he was born, Wyatt’s family and his medical team had an answer—TPI, or triosephosphate isomerase deficiency. TPI is an extremely rare genetic multisystem disorder first identified in 1964. Since that time, only […]

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